一项针对1型糖尿病青年成人吸烟习惯与微血管并发症的六年随访研究。
A six-year follow-up study of smoking habits and microvascular complications in young adults with type 1 diabetes.
作者信息
Sinha R N, Patrick A W, Richardson L, Wallymahmed M, MacFarlane I A
机构信息
Diabetes Centre, Walton Hospital, Liverpool.
出版信息
Postgrad Med J. 1997 May;73(859):293-4. doi: 10.1136/pgmj.73.859.293.
Abstract
One hundred insulin-dependent diabetic patients (age < 45 years, 53 smokers) were followed for six years. The age, duration of diabetes and mean glycated haemoglobin levels, were comparable between the smokers and non-smokers. Microvascular complications (retinopathy and increased urine albumin excretion) were commoner and more severe in the smoking group at six years, particularly in heavy smokers. Of the 45 original smokers reviewed at six years, 12 (27%) had stopped, six of whom had developed microvascular complications. Only two of the 'heavy' initial smokers, likely to be at most risk, had stopped smoking, and three original non-smokers had started smoking.
摘要
一百名胰岛素依赖型糖尿病患者（年龄<45岁，53名吸烟者）被随访了六年。吸烟者和非吸烟者之间的年龄、糖尿病病程和糖化血红蛋白平均水平相当。六年后，微血管并发症（视网膜病变和尿白蛋白排泄增加）在吸烟组中更为常见且更为严重，尤其是在重度吸烟者中。在六年时接受复查的45名原吸烟者中，12人（27%）已戒烟，其中6人出现了微血管并发症。最初的“重度”吸烟者中，最有可能面临最大风险的只有两人戒烟，而3名原不吸烟者开始吸烟。
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