Ampollini P, Marchesi C, Signifredi R, Maggini C
School of Psychiatry, University of Parma, Italy.
Acta Psychiatr Scand. 1997 May;95(5):420-3. doi: 10.1111/j.1600-0447.1997.tb09655.x.
Personality and temperament features, assessed with the Structured Interview for DSM-III-R Personality Disorders-Revised (SIDP-R) and the Tridimensional Personality Questionnaire (TPQ), respectively, were evaluated in 62 patients affected by panic disorder with (PD + MD) (n = 22) or without comorbid mood disorder (PD) (n = 40). A significant difference in the prevalence of personality disorders (PD + MD, 86% vs. PD, 62%; P < 0.05), particularly dependent (PD + DM, 50% vs. PD, 17%; P < 0.01) and borderline (PD + DM, 9% vs. PD, 0%; P = 0.05) personality disorders, was observed between the groups. Moreover, patients in the PD + MD group had higher scores for harm avoidance (PD + MD, 22.2 +/- 5.6 vs. PD, 26.9 +/- 5.1; P < 0.05) than patients in the PD group. The harm avoidance score in PD patients was significantly related to personality disorder and not to MD, suggesting that harm avoidance is not associated with greater severity of the illness. Our data confirm the hypothesis that subjects with higher harm avoidance scores have a greater probability of being affected by cluster C personality disorders and comorbid mood and anxiety disorders.
分别采用《精神疾病诊断与统计手册第三版修订本》人格障碍结构化访谈修订版（SIDP-R）和三维人格问卷（TPQ）对62例惊恐障碍患者进行人格和气质特征评估，其中伴有（PD+MD）（n=22）或不伴有共病情绪障碍（PD）（n=40）。两组间人格障碍患病率存在显著差异（PD+MD组为86%，PD组为62%；P<0.05），尤其是依赖型人格障碍（PD+DM组为50%，PD组为17%；P<0.01）和边缘型人格障碍（PD+DM组为9%，PD组为0%；P=0.05）。此外，PD+MD组患者的回避伤害得分高于PD组（PD+MD组为22.2±5.6，PD组为26.9±5.1；P<0.05）。PD患者的回避伤害得分与人格障碍显著相关，而与MD无关，这表明回避伤害与疾病的严重程度无关。我们的数据证实了这一假设，即回避伤害得分较高的受试者更有可能患C簇人格障碍以及共病情绪和焦虑障碍。
