转基因生物反应器的过去、现在与未来。
The past, present and future of transgenic bioreactors.
作者信息
Drohan W N
机构信息
J. Holland Laboratory, American Red Cross, Rockville, MD, USA.
出版信息
Thromb Haemost. 1997 Jul;78(1):543-7.
PMID:9198212
Abstract
Hybrid genes can control the tissue-specific synthesis of human proteins in transgenic animals. Thus, it is now possible to produce proteins of biomedical value in the body fluids or cells of transgenic livestock. In fact, the first transgenically produced protein, antithrombin III, is now in clinical trials and others will soon follow.
摘要
嵌合基因能够控制转基因动物中人类蛋白质的组织特异性合成。因此，现在有可能在转基因家畜的体液或细胞中生产具有生物医学价值的蛋白质。事实上，第一种转基因生产的蛋白质——抗凝血酶III，目前正在进行临床试验，其他蛋白质也将很快进入临床试验。
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