Möbius G
Zentralbl Allg Pathol. 1977;121(4-5):397-403.
The biological behaviour, the progression rate and the latency period of the carcinoma of the cervix uteri is discussed. We have tried to find out this by concluding indirectly and evaluating epidemiologically our own material, and considering the literature. Between 1967 and 1975 we bioptically diagnosed 1.933 in situ and 1.014 invasive cervial carcinomata. Among these there were 98 (9.7%) microcarcinomata. The average age of women with a carcinoma in situ in the years 1973-1975 was between 39 and 40 years. The average age of women with invasive carcinomata with the microcarcinoma excluded was 51-56 years. The average age of 98 women with a microcarcinoma during 1967--1975 was 47 years. The carcinoma in situ is a precursor of the invasive carcinoma in almost each case. The progression rate is approximately 30-50%. The latency period for the microcarcinoma is on a average of 7--10 years, till the clinical carcinoma 10--15 years. A reliable prognosis is impossible for the individual case.
本文讨论了子宫颈癌的生物学行为、进展速度和潜伏期。我们试图通过间接总结和流行病学评估我们自己的资料，并参考相关文献来找出这些情况。在1967年至1975年间，我们通过活检诊断出1933例原位癌和1014例浸润性宫颈癌。其中有98例（9.7%）微癌。1973 - 1975年原位癌女性患者的平均年龄在39至40岁之间。排除微癌后，浸润性癌女性患者的平均年龄为51至56岁。1967 - 1975年间98例微癌女性患者的平均年龄为47岁。原位癌几乎在每种情况下都是浸润性癌的前驱病变。进展速度约为30% - 50%。微癌的潜伏期平均为7 - 10年，直至临床癌出现则为10 - 15年。对于个体病例，可靠的预后是不可能的。
