Engel P J, Sabroe S
Hillerød Sygehus, patologist-anatontisk afdeling.
Ugeskr Laeger. 1997 May 19;159(21):3155-9.
This is a descriptive study of thymomas notified to the national Danish Cancer Registry and registered by the departments of pathology during the years 1943-1993. A total of 433 cases of benign and malignant thymomas were included over these 50 years with an increase of the incidence to a stable rate of 2.5/million/year from start to 1973. The male:female ratio is 1:1. While the age-specific incidence rate for persons below 40 years is constantly low throughout the period of investigation, a doubling of the rate is registered for persons between 70 and 79 during the period 1978-1993. The incidence rate in Copenhagen is much higher compared to other regions of Denmark. The above-mentioned increase in incidence is due mainly to an underreporting of benign thymomas during the first period of investigation (1943-1977), but may also be due to improved diagnostic capabilities and to more uniform methods of registration during the last period (1978-1993).
这是一项关于1943年至1993年间向丹麦国家癌症登记处报告并由病理科登记的胸腺瘤的描述性研究。在这50年中，共纳入了433例良性和恶性胸腺瘤病例，从开始到1973年发病率上升至稳定的每年2.5/百万。男女比例为1:1。在整个调查期间，40岁以下人群的年龄别发病率一直较低，而在1978年至1993年期间，70至79岁人群的发病率翻了一番。哥本哈根的发病率比丹麦其他地区高得多。上述发病率的上升主要是由于调查初期（1943 - 1977年）良性胸腺瘤报告不足，但也可能是由于诊断能力的提高以及最后阶段（1978 - 1993年）登记方法更加统一。
