Christensen J, Klarskov H, Raffin E, Gjerris F, Olsen J H
Sektor for kraeftepidemiologi, Kraeftens Bekaempelse, København.
Ugeskr Laeger. 1995 Oct 9;157(41):5716-20.
This is a descriptive study of primary intracranial and intraspinal tumours notified to the national Danish Cancer Registry during the years 1943-1987. A total of 19,317 cases of benign and malignant neoplasms were included over these 45 years with a doubling of the age-standardized incidence rates for both men and women from start till end of the registration period. The trend was mainly explained by markedly increasing rates in the age groups 60 years or above at diagnosis. Approximately some 74% of tumours were derived from the brain tissues and 19% from the intracranial and intraspinal meninges. Meningiomas predominate among women with a male:female ratio of 0.5, while tumours of the brain tissues predominate among men (ratio 1.3). Meningiomas are more frequently encountered as a chance finding at autopsy compared to other types of intracranial and intraspinal tumours. The above-mentioned increase in age-specific incidence is due mainly to improved diagnostic capabilities over the period and a subsequent decrease in the underreporting of these tumour types.
这是一项关于1943年至1987年间向丹麦国家癌症登记处报告的原发性颅内和脊髓内肿瘤的描述性研究。在这45年中，总共纳入了19317例良性和恶性肿瘤病例，在登记期开始到结束时，男性和女性的年龄标准化发病率均增加了一倍。这种趋势主要是由诊断时60岁及以上年龄组的发病率显著上升所解释的。大约74%的肿瘤起源于脑组织，19%起源于颅内和脊髓内的脑膜。脑膜瘤在女性中占主导地位，男女比例为0.5，而脑组织肿瘤在男性中占主导地位（比例为1.3）。与其他类型的颅内和脊髓内肿瘤相比，脑膜瘤在尸检时更常作为偶然发现。上述特定年龄发病率的增加主要是由于该时期诊断能力的提高以及随后这些肿瘤类型漏报情况的减少。
