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微小双股RNA病毒,一类新发现的未描述过的哺乳动物和鸟类病毒:一篇综述

Picobirnavirus, a novel group of undescribed viruses of mammals and birds: a minireview.

作者信息

Chandra R

机构信息

Department of Veterinary Microbiology, College of Veterinary Sciences, G.B. Pant University of Agriculture and Technology, U.S. Nagar (Nainital), U.P., India.

出版信息

Acta Virol. 1997 Feb;41(1):59-62.

PMID:9199719
Abstract

Picobirnavirus, a novel group of viruses recently detected in children and several species of animals including chickens, are different from the existing members of the family Birnaviridae. Picobirnavirus (PBV) is the tentatively proposed name for the group of these viruses. These viruses are 30-40 nm in diameter and have icosahedral symmetry with triangulation number (T) equal to 3. Their buoyant density in CsCl is 1.4 g/ml. Their genome is bi- or trisegmented double-stranded RNA (dsRNA) with segment lengths of 2.6 and 1.9 kbp for bisegmented and 2.9, 2.4 and 0.9 kbp for trisegmented genomes. The electrophoretic migration profile has considerable heterogeneity. PVBs are detected in diarrhoeic as well as non-diarrhoeic animals, hence, their potential needs further investigation.

摘要

微小双节段RNA病毒是最近在儿童以及包括鸡在内的几种动物中检测到的一类新型病毒,与双RNA病毒科的现有成员不同。微小双节段RNA病毒(PBV)是对这类病毒的暂定命名。这些病毒直径为30-40纳米,具有二十面体对称性,三角剖分数(T)等于3。它们在氯化铯中的浮力密度为1.4克/毫升。其基因组是双节段或三节段双链RNA(dsRNA),双节段基因组的片段长度为2.6和1.9千碱基对,三节段基因组的片段长度为2.9、2.4和0.9千碱基对。电泳迁移图谱具有相当大的异质性。在腹泻和非腹泻动物中均检测到了PVB,因此,它们的潜在影响需要进一步研究。

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