Lidgren L, Wallöe A
Acta Orthop Scand. 1977;48(4):356-61. doi: 10.3109/17453677708992008.
In 87 epileptics on diphenylhydantoin, the occurrence of non-seizure-related fractures, over a period of 7 years, was six times greater than that found in the normal population. The significant increase in fracture incidence was found to lie within the 45-64 age group indicating that eipleptics are not only more prone to fractures but also have an earlier fracture début.
在87名服用苯妥英钠的癫痫患者中,7年间非癫痫发作相关骨折的发生率比正常人群高6倍。骨折发生率的显著增加出现在45 - 64岁年龄组,这表明癫痫患者不仅更容易发生骨折,而且骨折初发年龄更早。