Johnell O, Nilsson B E, Wallöe A, Wiklund P E
Calcif Tissue Int. 1979 Oct 31;28(2):93-7. doi: 10.1007/BF02441225.
In 31 epileptics, most of whom had been on anticonvulsive drugs for decades, the amount of osteoid--active and inactive--and the osteoclast activity were measured in iliac crest biopsies and compared with the same variables from a control group. Although falling within normal limits, the amount of osteoid, in particular the inactive osteoid, was significantly increased in the epileptics. The osteoclast activity was also significantly increased in the epileptics.
在31名癫痫患者中，他们大多数已经服用抗惊厥药物数十年，对其髂嵴活检样本中的类骨质（活性和非活性）数量以及破骨细胞活性进行了测量，并与对照组的相同变量进行比较。尽管处于正常范围内，但癫痫患者的类骨质数量，尤其是非活性类骨质，显著增加。癫痫患者的破骨细胞活性也显著增加。
