Chen G Z, Fu D
Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 1996 Apr;16(4):221-3.
The normal intestinal migrating myoelectric complex (MMC) of rats recorded by implanted electrode consists of four phases (phase I, II, III and IV). After 8 Gy of gamma-radiation for 1 hour to 7 days, the MMC cycle in most of the rats were disappeared only phase I or II existed with minute's rhythm. 1 hour or 3 days after radiation, the MMC cycle appeared in a few rats with the phase II shortened significantly (P < 0.05). Results of observation on effect of Jiawei Sijunzi Decoction on MMC after radiation showed the changed phase and cycle of MMC were normalized basically by the medication. These results suggested that the Jiawei Sijunzi decoction could improve the intestinal disturbances caused by radiation, it might be one of the reason of its alleviating effect on the radiation diarrhea.
通过植入电极记录的大鼠正常肠移行性复合肌电（MMC）由四个阶段（I期、II期、III期和IV期）组成。给予大鼠8 Gy的γ射线照射1小时至7天后，大多数大鼠的MMC周期消失，仅存在以分钟为节律的I期或II期。照射后1小时或3天，少数大鼠出现MMC周期，II期明显缩短（P<0.05）。加味四君子汤对辐射后MMC影响的观察结果表明，用药后MMC的改变阶段和周期基本恢复正常。这些结果提示，加味四君子汤可改善辐射引起的肠道紊乱，这可能是其缓解放射性腹泻的原因之一。
