Provenzale D, Shearin M, Phillips-Bute B G, Drossman D A, Li Z, Tillinger W, Schmitt C M, Bollinger R R, Koruda M J
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.
Gastroenterology. 1997 Jul;113(1):7-14. doi: 10.1016/s0016-5085(97)70074-x.
BACKGROUND & AIMS: Health-related quality of life (HRQL) after proctocolectomy is a critical parameter for management decisions in patients with chronic pancolitis. The aim of this study was to evaluate the HRQL of patients with ileoanal pull-through and to validate new, easy-to-administer HRQL measures.
The Sickness Impact Profile (SIP), Short Form 36 (SF-36), Rating Form of Inflammatory Bowel Disease (IBD) Patient Concerns (RFIPC), and the time trade-off (TTO) were used to measure HRQL of pull-through patients. The SF-36 and the RFIPC were validated.
HRQL of patients with ileoanal pull-through was better than that of a national sample of patients with IBD (SIP and RFIPC) and similar to that of a normal population (SF-36). Physical and psychosocial subscales of the SF-36 correlated with the SIP, affirming the construct validity of the SF-36. The RFIPC results correlated with the SIP and SF-36 results, suggesting that it is also a valid health status measure for these patients. TTO results correlated with the physical subscales of the SIP and SF-36, reflecting the impact of physical health on this group.
HRQL of patients with ileoanal pull-through is excellent. The SF-36 and RFIPC are valid health status measures that can be used by clinicians and researchers in these patients.
全结肠直肠切除术后的健康相关生活质量（HRQL）是慢性全结肠炎患者管理决策的关键参数。本研究旨在评估回肠肛管拖出术患者的HRQL，并验证新的、易于实施的HRQL测量方法。
使用疾病影响量表（SIP）、简短健康调查问卷36项版本（SF-36）、炎症性肠病（IBD）患者关注评定量表（RFIPC）和时间权衡法（TTO）来测量拖出术患者的HRQL。对SF-36和RFIPC进行了验证。
回肠肛管拖出术患者的HRQL优于全国IBD患者样本（SIP和RFIPC），与正常人群相似（SF-36）。SF-36的身体和心理社会分量表与SIP相关，证实了SF-36的结构效度。RFIPC结果与SIP和SF-36结果相关，表明它也是这些患者有效的健康状况测量方法。TTO结果与SIP和SF-36的身体分量表相关，反映了身体健康对该组的影响。
回肠肛管拖出术患者的HRQL良好。SF-36和RFIPC是有效的健康状况测量方法，可供临床医生和研究人员用于这些患者。
