Haaker R G, Senkal M, Kielich T, Krämer J
Department of Orthopaedics, Ruhr University Hospital (St. Josef Hospital), Bochum, Germany.
Eur Spine J. 1997;6(2):98-101. doi: 10.1007/BF01358740.
Lumbar disc infection, either after surgical discectomy or caused by haematogenous spread from other infection sources, is a severe complication. Specific antibiotic treatment has to be started as soon as possible to obtain satisfactory results in conservative treatment or operative fusion. The aim of this study was to analyse 16 cases of lumbar disc infection, treated with percutaneous lumbar discectomy (PLD) to obtain adequate amounts of tissue for histological examination and microbial culture. Between 1990 and 1994, 26 patients with vertebral osteomyelitis were treated. Sixteen patients, with an average age of 41.4 years (range 14-59 years), underwent a diagnostic PLD. Eight of them showed only moderate changes on computed tomograms (CT scans) and magnetic resonance (MR) images in the initial stages of the disease. The other eight showed more or less extensive osteolytic lesions of one or both vertebral bodies adjacent to the involved disc. The histology results showed non-specific discitis in nine patients and tuberculosis in one. In two patients an open biopsy had been performed, which showed non-specific discitis. Microbiological analysis revealed specific infection in 45% of the patients. These patients received a specific antibiotic treatment after antibiogram for an average of 33 days. Only three patients were treated surgically, with evacuation of the disc space and interbody fusion; the whole group received a spondylitis brace. All patients obtained satisfactory clinical results at the last follow-up regarding pain, mobility and spontaneous fusion of the involved disc space. In conclusion, PLD is a very helpful minimally invasive procedure in conservative treatment of lumbar discitis.
腰椎间盘感染,无论是在手术椎间盘切除术后还是由其他感染源血行播散引起,都是一种严重的并发症。必须尽快开始特异性抗生素治疗,以便在保守治疗或手术融合中取得满意的效果。本研究的目的是分析16例腰椎间盘感染病例,采用经皮腰椎间盘切除术(PLD)获取足够的组织用于组织学检查和微生物培养。1990年至1994年间,26例椎体骨髓炎患者接受了治疗。16例平均年龄41.4岁(范围14 - 59岁)的患者接受了诊断性PLD。其中8例在疾病初期的计算机断层扫描(CT扫描)和磁共振(MR)图像上仅显示中度改变。另外8例在受累椎间盘相邻的一个或两个椎体显示或多或少广泛的骨质溶解病变。组织学结果显示9例为非特异性椎间盘炎,1例为结核。2例患者进行了开放活检,显示为非特异性椎间盘炎。微生物学分析显示45%的患者存在特异性感染。这些患者在获得抗菌谱后接受了平均33天的特异性抗生素治疗。仅3例患者接受了手术治疗,进行了椎间盘间隙清创和椎间融合;整个组都佩戴了脊柱炎支具。在最后一次随访时,所有患者在疼痛、活动度和受累椎间盘间隙的自发融合方面均取得了满意的临床结果。总之,PLD在腰椎间盘炎的保守治疗中是一种非常有用的微创手术。