Atkinson B A, Abu-Al-Jaibat A, LeBlanc D J
Department of Medicine, University of Texas Health Science Center at San Antonio, 78284, USA.
Antimicrob Agents Chemother. 1997 Jul;41(7):1598-600. doi: 10.1128/AAC.41.7.1598.
Two hundred twenty group D streptococci isolated from 1953 to 1954 from patients in the Washington, D.C., area were characterized. All were susceptible to ampicillin, vancomycin, and gentamicin; none produced beta-lactamase activity. High-level resistance to streptomycin was expressed by 117 strains, and 2 strains were resistant to >8 microg of chloramphenicol per ml. Three isolates were resistant to both erythromycin and lincomycin, and DNA from these hybridized to an ermAM probe. Of 118 strains resistant to tetracycline and minocycline, genomic DNA from 63 was examined for homology to tet(M), tet(O), and tet(S). DNA from 20 strains hybridized to tet(M), DNA from 37 strains hybridized to tet(S), and DNA from none of the strains hybridized to tet(O).
对1953年至1954年从华盛顿特区地区患者中分离出的220株D组链球菌进行了特性鉴定。所有菌株对氨苄西林、万古霉素和庆大霉素均敏感；无一产生β-内酰胺酶活性。117株菌株表现出对链霉素的高水平耐药性，2株对每毫升>8微克氯霉素耐药。3株分离株对红霉素和林可霉素均耐药，这些菌株的DNA与ermAM探针杂交。在118株对四环素和米诺环素耐药的菌株中，检测了63株菌株的基因组DNA与tet(M)、tet(O)和tet(S)的同源性。20株菌株的DNA与tet(M)杂交，37株菌株的DNA与tet(S)杂交，无一菌株的DNA与tet(O)杂交。
