氨基糖苷类对人多形核白细胞趋化反应的影响。
Effect of aminoglycosides on the chemotactic response of human polymorphonuclear leukocytes.
作者信息
Goodhart G L
出版信息
Antimicrob Agents Chemother. 1977 Oct;12(4):540-42. doi: 10.1128/AAC.12.4.540.
Abstract
Leukocyte chemotaxis was inhibited 9.6% compared with control in the presence of 10 mug of gentamicin per ml and 10.5% when exposed to 20 mug of amikacin per ml. However, cells incubated with an injectable form of gentamicin, containing preservatives, were inhibited an additional 25.8% relative to cells incubated with pure gentamicin.
摘要
在每毫升含有10微克庆大霉素的情况下，白细胞趋化性与对照组相比受到9.6%的抑制；当暴露于每毫升20微克阿米卡星时，白细胞趋化性受到10.5%的抑制。然而，与用纯庆大霉素孵育的细胞相比，用含有防腐剂的注射用庆大霉素孵育的细胞趋化性又额外受到25.8%的抑制。
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