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偏心滚轴式全人工心脏的试制

Trial manufacture of eccentric roller type total artificial heart.

作者信息

Sueshiro M, Fukunaga S, Mitsui N, Hirai S, Koura Y, Hotei H, Sueda T, Katsuhara K, Matsuura Y, Koguchi S

机构信息

First Department of Surgery, Hiroshima University School of Medicine, Japan.

出版信息

Artif Organs. 1997 Jul;21(7):735-8. doi: 10.1111/j.1525-1594.1997.tb03732.x.

Abstract

Working toward a completely implantable total artificial heart, we have designed an eccentric roller type total artificial heart. The actuator of this artificial heart is a drum type eccentric roller that squeezes the blood chambers. The blood chambers are made of silicone rubber and are torus in shape. The shape of the artificial heart is an almost circular cylinder, and its length and diameter are 10 cm and 8 cm, respectively. The 2 main characteristics of this artificial heart are that it discharges blood in a pulsatile mode and that it requires no reversing of the motor. Because we have not completed the artificial heart yet, we have tested the eccentric roller mechanism on the prototype with an overflow type mock circulation with a 100 mm Hg afterload. The prototype worked at the roller speeds of 50, 100, and 150 rpm with flow rates of 1.7, 3.7, and 5.4 L/min, respectively. Next the prototype was connected to a Donovan type mock circulatory system and worked at roller speeds of 88-214 rpm with flow rates of 3.0-8.4 L/min against mean afterloads of 82-120 mm Hg.

摘要

为了研发一种完全可植入的全人工心脏,我们设计了一种偏心滚轮式全人工心脏。这种人工心脏的驱动器是一个鼓型偏心滚轮,用于挤压血腔。血腔由硅橡胶制成,呈环形。人工心脏的形状近似圆柱体,其长度和直径分别为10厘米和8厘米。这种人工心脏的两个主要特点是它以脉动模式排出血液,并且不需要电机反转。由于我们尚未完成人工心脏的制作,我们在带有100毫米汞柱后负荷的溢流型模拟循环原型上测试了偏心滚轮机构。该原型在滚轮速度分别为50、100和150转/分钟时工作,流量分别为1.7、3.7和5.4升/分钟。接下来,将该原型连接到多诺万型模拟循环系统,并在滚轮速度为88 - 214转/分钟、流量为3.0 - 8.4升/分钟的情况下,在平均后负荷为82 - 120毫米汞柱的条件下工作。

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