胰十二指肠癌根治性切除术的随访研究
Follow-up studies of radical resection for pancreaticoduodenal cancer.
作者信息
Sato T, Saitoh Y, Noto N, Matsuno S
出版信息
Ann Surg. 1977 Nov;186(5):581-8. doi: 10.1097/00000658-197711000-00007.
Abstract
In a study of 66 patients with pancreaticoduodenal cancer with pancreaticoduodenectomy, there were five (7.5%) hospital deaths. Five-year survival rates were 7.8% in 20 patients with carcinoma of the head of the pancreas, 16.7% in 31 patients with carcinoma of the bile duct, and 38.5% in 15 patients with carcinoma of the ampulla of Vater. Fecal fat loss measured was 10 g or less per day in nine of 12 patients. Of the 19 patients having glucose tolerance tests, 13 showed abnormalities including the two who were diabetic. Operative findings which were indicative of a poor prognosis included lymph node metastases, macroscopic invasion of the tumor into the pancreatic capsule in patients with carcinoma of the head of the pancreas, the size of the tumor in those with carcinoma of the common bile duct, and direct invasion of the lesion into the pancreas in patients with carcinoma of the ampulla of Vater.
摘要
在一项针对66例行胰十二指肠切除术的胰十二指肠癌患者的研究中，有5例（7.5%）患者在医院死亡。20例胰头癌患者的5年生存率为7.8%，31例胆管癌患者为16.7%，15例 Vater壶腹癌患者为38.5%。12例患者中有9例测得的粪便脂肪丢失量每天为10克或更少。在19例进行葡萄糖耐量试验的患者中，13例显示异常，其中包括2例糖尿病患者。提示预后不良的手术发现包括淋巴结转移、胰头癌患者肿瘤肉眼侵犯胰腺包膜、胆总管癌患者肿瘤大小以及Vater壶腹癌患者病变直接侵犯胰腺。
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