Tobe H, Kubota M, Yamaguchi M, Kocha T, Aoyagi T
Showa College of Pharmaceutical Sciences, Tokyo, Japan.
Biosci Biotechnol Biochem. 1997 Jun;61(6):1027-9. doi: 10.1271/bbb.61.1027.
Humulone, a bone resorption inhibitor isolated from hop extract, induced apoptosis in the premyocytic leukemia cell line HL-60 between 1 and 100 micrograms/ml. Our data suggested that there was a correlation between the apoptosis-inducing activity of humulone and its antioxidative activity.
