电场中具有导电膜的球状细胞的电位分布。

Potential distribution for a spheroidal cell having a conductive membrane in an electric field.

作者信息

Jerry R A, Popel A S, Brownell W E

机构信息

Department of Otolaryngology-Head and Neck Surgery, John Hopkins University School of Medicine, Baltimore, MD 21205, USA.

出版信息

IEEE Trans Biomed Eng. 1996 Sep;43(9):970-2. doi: 10.1109/10.532132.

DOI:10.1109/10.532132

PMID:9214813

Abstract

When a cell is situated in a uniform electric field, the field is modified due to the relatively low conductance of the cell membrane compared to that of the surrounding fluids. In certain cases, such as in the estimation of internal and external electrokinetic forces, one requires a means of estimating the magnitude of the electric field inside and outside the cell. Most treatments consider the case when the membrane has zero conductivity, or the case of only a spherical cell. We solve Laplace's equation for the electric potential distribution inside and outside a cell having a prolate spheroidal shape and having a membrane with a finite, nonzero conductivity.

摘要

当一个细胞处于均匀电场中时，由于细胞膜的电导率相对于周围流体的电导率较低，电场会发生改变。在某些情况下，例如在估计内部和外部电动力量时，需要一种方法来估计细胞内外电场的大小。大多数处理方法考虑的是膜电导率为零的情况，或者仅为球形细胞的情况。我们求解拉普拉斯方程，以得到具有长椭球形且膜具有有限非零电导率的细胞内外的电势分布。