Markevich N I, Sel'kov E E
Biofizika. 1984 Sep-Oct;29(5):816-21.
A mathematical model of the ion transport across a membrane containing channel with inactivation has been analysed. Under certain conditions, such a membrane has been shown to behave as a selfoscillating circuit of a very high quality, its own frequency ranging for a variety of natural channels between 10(-1)-10(3) cycles. When exposed to an alternating electric field with a frequency approximating f0, the membrane displays resonance changes in its potential and channel conductivity. The average (over a period of forced oscillations) values of the potential and conductivity also show a resonance type of dependence on the frequency of the external field.
对包含具有失活特性通道的膜上离子转运的数学模型进行了分析。在某些条件下,已证明这样的膜表现为一个高品质的自振荡电路,其自身频率在各种天然通道中为10(-1)-10(3)次循环。当暴露于频率接近f0的交变电场时,膜在其电位和通道电导率方面表现出共振变化。电位和电导率的平均(在强制振荡期间)值也显示出对外部场频率的共振型依赖性。