Loebl M, Schwartz B
Arch Ophthalmol. 1977 Nov;95(11):1980-4. doi: 10.1001/archopht.1977.04450110074004.
Fluorescein angiograms of the optic disc were studied in 23 normal and 29 ocular hypertensive eyes. Significant differences in the frequency distributions of areas of defects were obtained between normal and ocular hypertensive eyes. Increased areas of filling defects were noted in ocular hypertensive eyes as compared to normals. There were also significant correlations of the areas of filling defects with age and systolic blood pressure in the ocular hypertensive eyes that were not present in the normals. These observations support the concept that fluorescein angiography of the optic disc demonstrates localized areas of impaired circulation that increase with ocular pressure, age, and systolic blood pressure. This technique may be useful in separating normal from the ocular hypertensive patient who shows changes in the circulation of the optic disc with increased ocular pressure.
对23只正常眼睛和29只高眼压眼睛进行了视盘荧光血管造影研究。正常眼睛和高眼压眼睛在缺损区域频率分布上存在显著差异。与正常眼睛相比，高眼压眼睛中充盈缺损区域增加。在高眼压眼睛中，充盈缺损区域与年龄和收缩压之间也存在显著相关性，而在正常眼睛中则不存在。这些观察结果支持这样一种概念，即视盘荧光血管造影显示出随着眼压、年龄和收缩压增加而出现的局部循环受损区域。这项技术可能有助于区分正常人与高眼压患者，后者在眼压升高时视盘循环会出现变化。
