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谵妄的转归:第2部分。可逆性认知功能障碍的临床特征——它们与公认的谵妄定义相同吗?

Outcome of delirium: part 2. Clinical features of reversible cognitive dysfunction--are they the same as accepted definitions of delirium?

作者信息

Treloar A J, Macdonald A J

机构信息

Section of Old Age Psychiatry, UMDS (Guy's) Bexley, UK.

出版信息

Int J Geriatr Psychiatry. 1997 Jun;12(6):614-8. doi: 10.1002/(sici)1099-1166(199706)12:6<614::aid-gps1553>3.0.co;2-x.

Abstract

OBJECTIVE

To describe the clinical features of reversible cognitive dysfunction.

DESIGN

Prospective cohort study.

SETTING

Acute geriatric inpatient units.

PATIENTS

A random sample of consecutive acute admissions of patients over the age of 65 (N = 80).

MAIN MEASUREMENTS

Serial assessments of mental state and cognitive function and observational data.

OUTCOME MEASURE

Patients with more than five points of 20% improvement in Mini Mental State Examination following the most severely impaired assessment operationally designated 'reversible cognitive dysfunction'. The clinical features of those with RCD are compared with those with non-reversible cognitive dysfunction.

MAIN RESULTS

Delusions, hallucinations, aggression, excitement, irritability and other 'active' symptoms were not commoner in RCD than in non-reversible cognitive dysfunction (non-RCD). By contrast, 'quiet' signs, such as plucking at bedclothes, poor attention, incoherent speech, abnormal associations, slow, vague thought and fluctuating mental state were more marked in RCD than in non-RCD.

CONCLUSIONS

Reversible cognitive dysfunction is a quiet and unobtrusive disorder.

摘要

目的

描述可逆性认知功能障碍的临床特征。

设计

前瞻性队列研究。

地点

老年急性住院病房。

患者

65岁以上连续急性入院患者的随机样本(N = 80)。

主要测量指标

精神状态和认知功能的系列评估以及观察数据。

结果指标

在最严重受损评估后,简易精神状态检查表得分提高超过20%达5分以上的患者,在操作上被定义为“可逆性认知功能障碍”。将可逆性认知功能障碍患者的临床特征与不可逆性认知功能障碍患者的特征进行比较。

主要结果

妄想、幻觉、攻击性、兴奋、易怒及其他 “活跃” 症状在可逆性认知功能障碍患者中并不比不可逆性认知功能障碍(非可逆性认知功能障碍)患者更常见。相比之下,“安静” 体征,如拉扯床单、注意力不集中、言语不连贯、联想异常、思维缓慢模糊及精神状态波动,在可逆性认知功能障碍患者中比在非可逆性认知功能障碍患者中更明显。

结论

可逆性认知功能障碍是一种隐匿的疾病。

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