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pSK41-like plasmid is necessary for Inc18-like vanA plasmid transfer from Enterococcus faecalis to Staphylococcus aureus in vitro.pSK41 样质粒对于粪肠球菌中 Inc18 样 vanA 质粒向金黄色葡萄球菌的体外转移是必需的。
Antimicrob Agents Chemother. 2013 Jan;57(1):212-9. doi: 10.1128/AAC.01587-12. Epub 2012 Oct 22.

本文引用的文献

1
Decreased susceptibility to vancomycin in meticillin-resistant Staphylococcus aureus: a 5 year study in an Indian tertiary hospital.
J Med Microbiol. 2010 Mar;59(Pt 3):375-376. doi: 10.1099/jmm.0.011940-0. Epub 2009 Dec 3.
2
Emergence of low level vancomycin resistance in MRSA.耐甲氧西林金黄色葡萄球菌中低水平万古霉素耐药性的出现。
Indian J Med Microbiol. 2003 Jul-Sep;21(3):196-8.
3
Emergence of vancomycin resistant Staphylococcus aureus (VRSA) from a tertiary care hospital from northern part of India.印度北部一家三级护理医院出现耐万古霉素金黄色葡萄球菌（VRSA）。
BMC Infect Dis. 2006 Oct 26;6:156. doi: 10.1186/1471-2334-6-156.
4
Heterologous expression of the enterococcal vanA operon in methicillin-resistant Staphylococcus aureus.肠球菌vanA操纵子在耐甲氧西林金黄色葡萄球菌中的异源表达。
Antimicrob Agents Chemother. 2004 Nov;48(11):4281-5. doi: 10.1128/AAC.48.11.4281-4285.2004.
5
Vancomycin-resistant Staphylococcus aureus in the absence of vancomycin exposure.未接触万古霉素情况下的耐万古霉素金黄色葡萄球菌
Clin Infect Dis. 2004 Apr 15;38(8):1049-55. doi: 10.1086/382357. Epub 2004 Mar 24.
6
Staphylococcus aureus with heterogeneous resistance to vancomycin: epidemiology, clinical significance, and critical assessment of diagnostic methods.对万古霉素具有异质性耐药的金黄色葡萄球菌：流行病学、临床意义及诊断方法的批判性评估
Antimicrob Agents Chemother. 2003 Oct;47(10):3040-5. doi: 10.1128/AAC.47.10.3040-3045.2003.
7
Coexistence of vancomycin-resistant enterococci and Staphylococcus aureus in the intestinal tracts of hospitalized patients.住院患者肠道中耐万古霉素肠球菌与金黄色葡萄球菌的共存。
Clin Infect Dis. 2003 Oct 1;37(7):875-81. doi: 10.1086/377451. Epub 2003 Sep 12.
8
Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance gene.感染含有vanA耐药基因的耐万古霉素金黄色葡萄球菌。
N Engl J Med. 2003 Apr 3;348(14):1342-7. doi: 10.1056/NEJMoa025025.
9
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.使用实时定量PCR和2(-ΔΔC(T))方法分析相对基因表达数据。
Methods. 2001 Dec;25(4):402-8. doi: 10.1006/meth.2001.1262.
10
Increasing resistance to vancomycin and other glycopeptides in Staphylococcus aureus.金黄色葡萄球菌对万古霉素和其他糖肽类抗生素的耐药性不断增加。
Emerg Infect Dis. 2001 Mar-Apr;7(2):327-32. doi: 10.3201/eid0702.010237.

在印度北部一家三级护理中心，万古霉素中介金黄色葡萄球菌菌株的定植，这些菌株含有 vanA 耐药基因。

Colonization with vancomycin-intermediate Staphylococcus aureus strains containing the vanA resistance gene in a tertiary-care center in north India.

机构信息

Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

出版信息

J Clin Microbiol. 2012 May;50(5):1730-2. doi: 10.1128/JCM.06208-11. Epub 2012 Feb 15.

DOI:10.1128/JCM.06208-11
PMID:22337975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3347155/
Abstract

A nasal carriage survey for methicillin-resistant Staphylococcus aureus (MRSA) in an intensive care unit detected four strains of MRSA with reduced susceptibility to vancomycin. The vanA gene was found in two of these vancomycin-intermediate Staphylococcus aureus (VISA) strains. The absence of selective vancomycin pressure might have resulted in reduced expression of the resistant gene.

摘要

在重症监护病房进行的耐甲氧西林金黄色葡萄球菌（MRSA）鼻腔携带调查中，发现了四株对万古霉素敏感性降低的 MRSA。其中两株万古霉素中介金黄色葡萄球菌（VISA）菌株中发现了 vanA 基因。缺乏选择性万古霉素压力可能导致耐药基因表达降低。