在印度北部一家三级护理中心，万古霉素中介金黄色葡萄球菌菌株的定植，这些菌株含有 vanA 耐药基因。
Colonization with vancomycin-intermediate Staphylococcus aureus strains containing the vanA resistance gene in a tertiary-care center in north India.
机构信息
Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.
出版信息
J Clin Microbiol. 2012 May;50(5):1730-2. doi: 10.1128/JCM.06208-11. Epub 2012 Feb 15.
Abstract
A nasal carriage survey for methicillin-resistant Staphylococcus aureus (MRSA) in an intensive care unit detected four strains of MRSA with reduced susceptibility to vancomycin. The vanA gene was found in two of these vancomycin-intermediate Staphylococcus aureus (VISA) strains. The absence of selective vancomycin pressure might have resulted in reduced expression of the resistant gene.
摘要
在重症监护病房进行的耐甲氧西林金黄色葡萄球菌（MRSA）鼻腔携带调查中，发现了四株对万古霉素敏感性降低的 MRSA。其中两株万古霉素中介金黄色葡萄球菌（VISA）菌株中发现了 vanA 基因。缺乏选择性万古霉素压力可能导致耐药基因表达降低。
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