Daidone M G, Silvestrini R, Benini E, Grigioni W F, D'Errico A
Oncologia Sperimentale C, Istituto Nazionale per lo Studio e la Cura del Tumori, Milano, Italy.
Br J Cancer. 1997;76(1):52-3. doi: 10.1038/bjc.1997.335.
The presence of high-affinity 67-kDa laminin receptors, detected immunohistochemically, was determined on 63 primary breast cancers and on metachronous metastatic lesions or contralateral cancers from the same patients. A disagreement was observed in two-thirds of the cases. In particular, laminin receptor content was significantly lower (P = 0.02) in local recurrences and slightly higher in lymph node metastasis than in the corresponding primary tumours.
通过免疫组织化学检测，在63例原发性乳腺癌以及来自同一患者的异时性转移病灶或对侧癌中，测定了高亲和力67 kDa层粘连蛋白受体的存在情况。在三分之二的病例中观察到了差异。特别是，局部复发中laminin受体含量显著较低（P = 0.02），而淋巴结转移中的含量比相应的原发性肿瘤略高。
