Defective neutrophil function in workers occupationally exposed to hexachlorobenzene.
作者信息
Queiroz M L, Bincoletto C, Perlingeiro R C, Souza C A, Toledo H
机构信息
Department of Pharmacology/Hemocentre, F.C.M., State University of Campinas, Brazil.
出版信息
Hum Exp Toxicol. 1997 Jun;16(6):322-6. doi: 10.1177/096032719701600605.
PMID:9219028
Abstract
In this work we have studied the respiratory burst and chemotaxis of polymorphonuclear leukocytes from 51 workers exposed to chlorinated compounds, which were compared with those of non-exposed, age- and sex-matched individuals. These two neutrophil functions were significantly reduced as compared to controls. No correlation was observed between the length of exposure, hexachlorobenzene (HCB) blood concentrations and neutrophil chemotaxis or the extent of nitroblue tetrazolium reduction.
摘要
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