Jampol L M, Orth D, Daily M J, Rabb M F
Am J Ophthalmol. 1979 Oct;88(4):683-9. doi: 10.1016/0002-9394(79)90665-2.
Three patients with geographic choroiditis developed subretinal neovascular membranes associated with subretinal hemorrhage and serous elevation of the retina. Proximity of the membrane to the foveal avascular zone prevented photocoagulation of the neovascular membrane in one patient. Central visual acuity remained 6/60 (20/200) despite systemic corticosteroid therapy. The neovascular membranes in the other two patients were obliterated by argon laser photocoagulation with preservation of central vision. The inflammatory process of geographic choroiditis can disrupt Bruch's membrane, allowing occasional choroidal vascular growth. Concomitant destruction of choroidal vessels may account for rarity of subretinal neovascularization in geographic choroiditis.
三名地图状脉络膜炎患者发生了视网膜下新生血管膜,并伴有视网膜下出血和视网膜浆液性隆起。在一名患者中,新生血管膜靠近黄斑无血管区,无法对其进行光凝治疗。尽管进行了全身皮质类固醇治疗,中心视力仍为6/60(20/200)。另外两名患者的新生血管膜通过氩激光光凝得以封闭,中心视力得以保留。地图状脉络膜炎的炎症过程可破坏布鲁赫膜,偶尔会使脉络膜血管生长。脉络膜血管的同时破坏可能是地图状脉络膜炎中视网膜下新生血管形成罕见的原因。