老年人对流感疫苗产生血清抗体最早峰值反应的时间。
Time to earliest peak serum antibody response to influenza vaccine in the elderly.
作者信息
Gross P A, Russo C, Dran S, Cataruozolo P, Munk G, Lancey S C
机构信息
Department of Internal Medicine, Hackensack University Medical Center, New Jersey 07601, USA.
出版信息
Clin Diagn Lab Immunol. 1997 Jul;4(4):491-2. doi: 10.1128/cdli.4.4.491-492.1997.
Abstract
The earliest time at which serum antibody levels peak following administration of an influenza virus vaccine in elderly persons is not clearly defined. We compared the time intervals of 1 and 2 weeks after vaccination. A commercial trivalent vaccine containing the hemagglutinins of influenza viruses A/Texas/36/91 (H1N1), A/Johannesburg/33/94 (H3N2), and B/Harbin/7/94 was used. The hemagglutination inhibition (HAI) antibody titers at 1 week after vaccination were significantly lower than the HAI titers at 2 weeks postvaccination for all three vaccine components.
摘要
老年人接种流感病毒疫苗后血清抗体水平达到峰值的最早时间尚未明确界定。我们比较了接种疫苗后1周和2周的时间间隔。使用了一种包含甲型流感病毒A/德州/36/91（H1N1）、A/约翰内斯堡/33/94（H3N2）和乙型流感病毒B/哈尔滨/7/94血凝素的市售三价疫苗。对于所有三种疫苗成分，接种疫苗后1周时的血凝抑制（HAI）抗体滴度显著低于接种疫苗后2周时的HAI滴度。
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Time to peak serum antibody response to influenza vaccine in the elderly.老年人对流感疫苗血清抗体反应达到峰值的时间。
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