Rastogi S, Gross P A, Bonelli J, Dran S, Levandowski R A, Russo C, Weksler M E, Kaye D, Levison M, Abrutyn E
Department of Internal Medicine, Hackensack Medical Center, New Jersey 07601.
Clin Diagn Lab Immunol. 1995 Jan;2(1):120-1. doi: 10.1128/cdli.2.1.120-121.1995.
The time to the appearance of a peak serum antibody response to influenza virus vaccine is not clearly defined. We compared the most commonly used time intervals described in the literature--4 and 6 weeks after vaccination. We studied 118 elderly patients from three different geographic sites. The 1992 to 1993 trivalent inactivated influenza virus vaccine containing influenza virus A/Beijing/353/89 (H3N2), influenza virus A/Texas/36/91 (H1N1), and influenza virus B/Panama/45/90 was used. No statistically significant differences were found at the 4- and 6-week intervals after vaccination.
血清对流感病毒疫苗产生抗体反应峰值的时间尚无明确定义。我们比较了文献中描述的最常用时间间隔——接种疫苗后4周和6周。我们研究了来自三个不同地理区域的118名老年患者。使用了1992至1993年的三价灭活流感病毒疫苗,其包含甲型流感病毒A/北京/353/89(H3N2)、甲型流感病毒A/得克萨斯/36/91(H1N1)和乙型流感病毒B/巴拿马/45/90。接种疫苗后4周和6周时未发现统计学上的显著差异。