Gross P A, Russo C, Teplitzky M, Dran S, Cataruozolo P, Munk G
Department of Internal Medicine, Hackensack University Medical Center, New Jersey 07601, USA.
Clin Diagn Lab Immunol. 1996 May;3(3):361-2. doi: 10.1128/cdli.3.3.361-362.1996.
The earliest time at which serum antibody peaks following administration of influenza virus vaccine in elderly persons is not clearly defined. We compared the time intervals of 2 and 4 weeks after vaccination. A commercial trivalent vaccine containing the hemagglutinins of influenza viruses A/Texas/36/91(H1N1), A/Shangdong/9/93(H3N2), and B/Panama/45/90 was used. The hemagglutination inhibition antibody titers at 2 weeks after vaccination were identical to the hemagglutination inhibition antibody titers at 4 weeks for all three vaccine components.
老年人接种流感病毒疫苗后血清抗体达到峰值的最早时间尚无明确定义。我们比较了接种疫苗后2周和4周的时间间隔。使用了一种包含甲型流感病毒A/德州/36/91(H1N1)、A/山东/9/93(H3N2)和乙型流感病毒B/巴拿马/45/90血凝素的市售三价疫苗。对于所有三种疫苗成分,接种疫苗后2周时的血凝抑制抗体滴度与4周时的血凝抑制抗体滴度相同。