Sumiya H, Kobayashi K, Mizukoshi C, Aoki T, Koshino Y, Taki J, Tonami N
Department of Nuclear Medicine, Kanazawa University School of Medicine, Japan.
J Nucl Med. 1997 Jul;38(7):1120-2.
SPECT imaging brain perfusion using 99mTc-HMPAO was performed on a 38-yr-old women with Lyme neuroborreliosis confirmed by autopsy. The patient had been suspected of spinocerebellar degeneration. Cerebral blood flow was diffusely decreased throughout cerebral cortices but cerebellar blood flow was not impaired, which indicated that the diagnosis was unlikely spinocerebellar degeneration. These findings suggested that brain perfusion SPECT provides useful information in diagnosing the patients with Lyme neuroborreliosis, especially when spinocerebellar degeneration is included in the differential diagnosis.
对一名经尸检确诊为莱姆病神经伯氏疏螺旋体病的38岁女性进行了使用99mTc-HMPAO的单光子发射计算机断层扫描(SPECT)脑灌注成像。该患者曾被怀疑患有脊髓小脑变性。全脑皮质的脑血流量普遍减少,但小脑血流量未受损害,这表明诊断不太可能是脊髓小脑变性。这些发现提示,脑灌注SPECT在诊断莱姆病神经伯氏疏螺旋体病患者时提供了有用信息,尤其是在鉴别诊断中包括脊髓小脑变性时。