Uygur G A, Liu Y, Hellman R S, Tikofsky R S, Collier B D
Department of Radiology, Medical College of Wisconsin, Milwaukee 53226, USA.
J Nucl Med. 1995 Apr;36(4):610-2.
Fahr's disease is histopathologically characterized by massive bilateral calcifications of the cerebral basal ganglia, the dentate nuclei of the cerebellum and both the cerebral and cerebellar cortices. We report a case of Fahr's disease in which a 99mTc-hexamethyl-propylenamine oxime (99mTc-HMPAO) brain SPECT study was used to evaluate regional cerebral blood flow to the calcified regions. There was markedly decreased perfusion to the basal ganglia bilaterally as well as decreased perfusion to the cerebral cortices that correlated well with the patient's clinical condition.
法尔病的组织病理学特征是双侧大脑基底神经节、小脑齿状核以及大脑和小脑皮质出现大量钙化。我们报告一例法尔病病例，该病例使用99m锝-六甲基丙烯胺肟（99mTc-HMPAO）脑单光子发射计算机断层扫描（SPECT）研究来评估钙化区域的局部脑血流。双侧基底神经节灌注明显减少，大脑皮质灌注也减少，这与患者的临床状况密切相关。
