树懒分离脂肪细胞的葡萄糖代谢
Glucose metabolism by isolated fat cells from sloth.
作者信息
Chiappe de Cingolani G E, do Carmo de Araujo Fraga M, de Menezes Lima V L
出版信息
Arch Int Physiol Biochim. 1979 Feb;87(1):65-71. doi: 10.3109/13813457909070486.
Glucose metabolism by sloth fat cells with and without addition of insulin was investigated. The data were compared to the results obtained with rat fat cells incubated under the same experimental conditions. Sloth fat cells showed a very low glucose oxidation to 14CO2 and incorporation into total lipids. The glucose incorporated into lipids is mainly in the glyceride-glycerol moiety. Addition of insulin did not produce an increase on glucose oxidation and a slight increase in the incorporation into total lipids was observed. Since it has been reported that sloths have a very low rate on thyroxine secretion, the results are discussed in relation to data in the literature on carbohydrate and lipid metabolism in hypothyroid animals.
研究了添加和不添加胰岛素时树懒脂肪细胞的葡萄糖代谢情况。将这些数据与在相同实验条件下培养的大鼠脂肪细胞所得到的结果进行了比较。树懒脂肪细胞对葡萄糖氧化为(^{14}CO_2)以及葡萄糖掺入总脂质的能力非常低。掺入脂质中的葡萄糖主要存在于甘油酯 - 甘油部分。添加胰岛素并未使葡萄糖氧化增加，仅观察到掺入总脂质的量略有增加。由于已有报道称树懒的甲状腺素分泌率非常低，因此结合文献中关于甲状腺功能减退动物碳水化合物和脂质代谢的数据对这些结果进行了讨论。
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