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[麻醉期间的伦理冲突。手术室中的“不要复苏”医嘱]

[Ethical conflicts during anesthesia. "Do not resuscitate" orders in the operating room].

作者信息

Mohr M

机构信息

Zentrum Anaesthesiologie, Rettungs- und Intensivmedizin, Georg-August-Universität Göttingen.

出版信息

Anaesthesist. 1997 Apr;46(4):267-74. doi: 10.1007/s001010050400.

DOI:10.1007/s001010050400
PMID:9229979
Abstract

Patients have the right to make decisions concerning their health care. The right to consent to or refuse treatment is based on the ethical principle of autonomy. Respecting a patient's autonomy has emerged as one of the leading principle in medical ethics in the last years. In the United States, the Patient Self-Determination Act of 1991 stated that all patients admitted to hospital have to be informed about their right to prepare advance directives and to refuse life-prolonging treatment. Do-not-resuscitate (DNR) orders have been established to provide a mechanism for withholding specific resuscitative therapies in the event of cardiac arrest. Patients may write DNR orders to express in advance their preferences at a time when they are capable of making informed decisions. Terminally ill patients may need palliative surgical interventions to relieve pain or facilitate care. In patients with DNR orders undergoing anaesthesia and surgical procedures, the DNR status in the operating room is increasingly a matter of ethical conflict. Anaesthetic care virtually always implies the provision of resuscitative measures if necessary. Interventions like intubation, mechanical ventilation, or administration of vasoactive drugs may be regarded as a part of resuscitative efforts. There is a remarkable lack of consistency in policies and practices in hospitals regarding interpretation of DNR orders during the perioperative period. Considering policies automatically suspending DNR orders prior to anaesthetic care, the American Society of Anesthesiologists (ASA) in 1993 introduced "Ethical guidelines for the anesthesia care of patients with do not resuscitate orders or other directives that limit treatment". To address a patient's right to self-determination in a responsible and ethical way, the ASA recommends explicitly discussing with the patient all limitations of therapeutic interventions. A list of relevant items that should be considered, like defibrillation and chest compression, but also blood product transfusion or the administration of antibiotics, has been provided by the ASA. These statements can provide some order to an increasing state of the uncertainty, but guidelines might also be regarded as imposing restrictions that compromise the anaesthesiologist's autonomy. I believe that defining accepted and refused interventions in advance is not an appropriate approach to DNR orders during anaesthesia and surgery, as it will be difficult to find a definition of what constitutes resuscitation in this context. Communication with the patient and exchange of information are essential factors promoting ethical decisions. Knowing the individual patient's preferences and fears, a more suitable approach seems to be the perioperative suspension of the DNR order for a limited period of time, with the assurance that therapeutic procedures instituted during surgery will be discontinued postoperatively in reconsideration of the DNR order and if the underlying disease process turns out to be non-reversible.

摘要

患者有权就其医疗保健做出决定。同意或拒绝治疗的权利基于自主的伦理原则。在过去几年中,尊重患者的自主权已成为医学伦理的主要原则之一。在美国,1991年的《患者自主决定法案》规定,所有入院患者都必须被告知他们有权制定预先医疗指示并拒绝延长生命的治疗。已经制定了“不要复苏”(DNR)医嘱,以便在心脏骤停时提供一种机制来停止特定的复苏治疗。患者可以签署DNR医嘱,在他们能够做出明智决定时提前表达自己的偏好。晚期患者可能需要姑息性手术干预来缓解疼痛或便于护理。对于正在接受麻醉和外科手术的签署了DNR医嘱的患者,手术室中的DNR状态越来越成为一个伦理冲突问题。麻醉护理实际上几乎总是意味着在必要时提供复苏措施。诸如插管、机械通气或使用血管活性药物等干预措施可能被视为复苏努力的一部分。医院在围手术期对DNR医嘱的解释方面,政策和实践明显缺乏一致性。考虑到一些政策会在麻醉护理前自动暂停DNR医嘱,美国麻醉医师协会(ASA)在1993年出台了“关于对有不要复苏医嘱或其他限制治疗指令的患者进行麻醉护理的伦理指南”。为了以负责和符合伦理的方式处理患者的自主决定权,ASA建议与患者明确讨论治疗干预的所有限制。ASA提供了一份应考虑的相关项目清单,如除颤和胸外按压,还有血液制品输血或抗生素的使用。这些声明可以为日益增加的不确定性带来一定秩序,但指南也可能被视为施加了限制,损害了麻醉医师的自主权。我认为,在麻醉和手术期间,预先确定接受和拒绝的干预措施并非处理DNR医嘱的合适方法,因为在此背景下很难找到构成复苏的定义。与患者沟通和信息交流是促进符合伦理决策的关键因素。了解患者个人的偏好和恐惧后,一种更合适的方法似乎是在围手术期有限时间内暂停DNR医嘱,并保证在重新考虑DNR医嘱且如果潜在疾病过程被证明是不可逆的情况下,手术期间实施的治疗程序将在术后停止。

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本文引用的文献

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Cardiac arrest: prognostic factors and outcome at one year.心脏骤停:一年时的预后因素及结局
Resuscitation. 1993 Apr;25(2):171-9. doi: 10.1016/0300-9572(93)90093-6.
2
Do-not-resuscitate orders in the operating room.手术室中的“不要复苏”医嘱。
AORN J. 1993 Apr;57(4):947-51. doi: 10.1016/s0001-2092(07)69098-x.
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Selective application of cardiopulmonary resuscitation improves survival rates.选择性应用心肺复苏可提高生存率。
Anesth Analg. 1993 Mar;76(3):478-84. doi: 10.1213/00000539-199303000-00005.
4
"Do not resuscitate" (DNR) orders and the anesthesiologist: a survey.“不要复苏”(DNR)医嘱与麻醉医生:一项调查
Anesth Analg. 1993 Feb;76(2):394-401.
5
What does "resuscitate" mean in a do-not-resuscitate (DNR) order?在“不要进行心肺复苏”(DNR)医嘱中,“resuscitate”是什么意思?
Anesth Analg. 1993 Jan;76(1):206-7. doi: 10.1213/00000539-199301000-00044.
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Suspending do-not-resuscitate orders during anesthesia and surgery.在麻醉和手术期间暂停“不要复苏”医嘱。
Surg Neurol. 1993 Jul;40(1):7-9. doi: 10.1016/0090-3019(93)90161-s.
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Outcome of cardiopulmonary resuscitation and predictors of resuscitation status in an urban community teaching hospital.城市社区教学医院心肺复苏的结果及复苏状态的预测因素
Resuscitation. 1994 Jan;27(1):13-21. doi: 10.1016/0300-9572(94)90016-7.
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"Do not resuscitate" (DNR) orders in the perioperative period--a comparison of the perspectives of anesthesiologists, internists, and surgeons.围手术期的“不要复苏”(DNR)医嘱——麻醉医生、内科医生和外科医生观点的比较
Anesth Analg. 1994 Apr;78(4):651-8. doi: 10.1213/00000539-199404000-00006.
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Do not resuscitate (DNR) orders during surgery: ethical foundations for institutional policies in the United States.手术期间的“不要复苏”(DNR)医嘱:美国机构政策的伦理基础
Anesth Analg. 1995 Apr;80(4):806-9. doi: 10.1097/00000539-199504000-00027.
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Ethical dilemmas and decisions concerning the do-not-resuscitate patient undergoing anesthesia.关于接受麻醉的“不要复苏”患者的伦理困境与决策。
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