Lesnik O M, Istomina O Iu, Rijpkema S, Bruininck H, Beliaeva M L
Ter Arkh. 1997;69(5):9-12.
A parallel study was made of the clinical spectrum of Lyme borreliosis in the Middle Urals and genetic species of the causative agent (Borrelia burgdorferi) in the ticks collected at the same territory. Clinical picture of Lyme borreliosis in the Middle Urals is different from that in America but had similar features with European borreliosis: nervous disorders were more frequent than arthritis, high incidence of the symptoms in segments close to the place of the agent inoculation, low occurrence of secondary erythema and carditis. The collected ticks were Ixodes persulcatus. They carried B. garinii, B. afzelii, VS116 typical for Europe. B. burgdorferi sensu stricto characteristic for USA where arthritis was most common among the symptoms was not detected. Thus, the findings confirm suggestions on association of Lyme borreliosis clinical polymorphism in various geographic zones with genetic heterogeneity of the causative agent.
对中乌拉尔地区莱姆病的临床谱与在同一地区采集的蜱虫中病原体（伯氏疏螺旋体）的基因种类进行了平行研究。中乌拉尔地区莱姆病的临床表现与美国不同，但与欧洲莱姆病有相似特征：神经紊乱比关节炎更常见，病原体接种部位附近节段症状的发生率高，继发性红斑和心肌炎的发生率低。采集的蜱虫为全沟硬蜱。它们携带欧洲常见的伽氏疏螺旋体、阿氏疏螺旋体、VS116。未检测到在美国症状中最常见的狭义伯氏疏螺旋体。因此，这些发现证实了关于不同地理区域莱姆病临床多态性与病原体基因异质性之间关联的推测。
