van Gelder C W, Flurkey W H, Wichers H J
Agrotechnological Research Institute (ATO-DLO), Wageningen, The Netherlands.
Phytochemistry. 1997 Aug;45(7):1309-23. doi: 10.1016/s0031-9422(97)00186-6.
Tyrosinases from various organisms are compared with respect to enzymatic structure, primary, secondary and tertiary structure, domain structure, Cu binding sites, maturation mechanism and activation mechanism. On the basis of these comparisons, and by using hemocyanin structure as a template, a structure model for the active site of tyrosinases is proposed.
对来自各种生物体的酪氨酸酶在酶结构、一级、二级和三级结构、结构域结构、铜结合位点、成熟机制和激活机制方面进行了比较。基于这些比较，并以血蓝蛋白结构为模板，提出了酪氨酸酶活性位点的结构模型。
