Liu Y J, Banchereau J
Laboratory for Immunological Research, Schering-Plough, Dardilly, 69571, France.
Semin Immunol. 1997 Aug;9(4):235-40. doi: 10.1006/smim.1997.0080.
During humoral immune responses, B-lymphocyte activation is followed by differentiation along either the plasma cell pathway or the memory B-cell pathway. Recent studies suggest that CD40-CD40 ligand, OX-OX40 ligand, a group of cytokines and intracellular transcriptional factors may all contribute to B-lymphocyte differentiation control.
在体液免疫反应过程中,B淋巴细胞激活后会沿着浆细胞途径或记忆B细胞途径分化。最近的研究表明,CD40-CD40配体、OX-OX40配体、一组细胞因子和细胞内转录因子可能都有助于控制B淋巴细胞的分化。