Heddle N, Kelton J G, Smaill F, Foss K, Everson J, Janzen C, Walker C, Jones M, Hammons D
Department of Pathology, McMaster University, Hamilton, Ont.
CMAJ. 1997 Jul 15;157(2):149-54.
To describe the process used to notify pediatric patients who received transfusions of blood or blood products at our institution before donor blood was routinely screened for antibodies to HIV (1985) and hepatitis C virus (1990), and to evaluate the effectiveness of the notification program.
Patients who had received transfusions were identified through the hospital's medical records and the records from the Transfusion Medicine Laboratory. Patients were contacted by registered mail to provide notification of transfusion. A questionnaire was included with the notification to obtain information about the patient's awareness of the transfusion and whether he or she had undergone or planned to undergo testing for HIV and hepatitis C virus.
Tertiary care university-affiliated teaching hospital in Hamilton, Ont.
Patients 16 years of age or younger who had received blood products between February 1978 and November 1985. Patients who had received only albumin or immune serum globulin were not included as these products were not associated with viral transmission in Canada.
Notification letters were sent to 1546 patients. Of these letters 522 (33.8%) were returned undelivered. Of the 1024 patients contacted 493 (48.1%) responded to the questionnaire, of whom 157 (31.8%) were not aware of their transfusion. A total of 130 (26.4%) of the respondents had already undergone testing for HIV, and 342 (69.4%) indicated that they would undergo such testing as a result of the notification. In contrast, only 30 (6.3%) of 474 respondents had undergone testing for hepatitis C virus, but 425 (89.7%) indicated that they would undergo such testing. Overall, the patients' response to the notification was neutral or positive; however, a number of patients expressed dissatisfaction and anxiety.
The high proportion of patients who were unaware that they had undergone transfusion and who decided to undergo testing for HIV and hepatitis C virus as a result of notification supports the use of notification programs such as this one.
描述在我院对在常规筛查献血者HIV抗体（1985年）和丙型肝炎病毒抗体（1990年）之前接受输血或血液制品的儿科患者进行通知的过程，并评估该通知计划的有效性。
通过医院病历和输血医学实验室记录识别接受过输血的患者。通过挂号信联系患者以提供输血通知。通知中包含一份问卷，以获取患者对输血的知晓情况以及他或她是否已经接受或计划接受HIV和丙型肝炎病毒检测的信息。
安大略省汉密尔顿市的一所大学附属三级护理教学医院。
1978年2月至1985年11月期间接受过血液制品的16岁及以下患者。仅接受白蛋白或免疫血清球蛋白的患者不包括在内，因为这些产品在加拿大与病毒传播无关。
向1546名患者发送了通知信。其中522封（33.8%）被退回未送达。在联系的1024名患者中，493名（48.1%）回复了问卷，其中157名（31.8%）不知道自己接受过输血。共有130名（26.4%）受访者已经接受了HIV检测，342名（69.4%）表示他们将因通知而接受此类检测。相比之下，474名受访者中只有30名（6.3%）接受过丙型肝炎病毒检测，但425名（89.7%）表示他们将接受此类检测。总体而言，患者对通知的反应是中性或积极的；然而，一些患者表达了不满和焦虑。
大量患者不知道自己接受过输血，并且因通知而决定接受HIV和丙型肝炎病毒检测，这支持了使用此类通知计划。
