Lees J
Clatterbridge centre for oncology, Bebington, Wirral, Merseyside, UK.
Eur J Cancer Care (Engl). 1997 Mar;6(1):45-9. doi: 10.1111/j.1365-2354.1997.tb00268.x.
The aim of this prospective two year study was to compare the outcome of two methods of nutritional support, namely nasogastric [NG] and percutaneous endoscopic gastrostomy [PEG] feeding implemented for head and neck cancer patients unable to maintain their nutritional status whilst receiving radiotherapy treatment at a regional oncology unit. The nutritional requirements of the 100 patients included in the study were calculated and an enteral feeding regime implemented to ensure the nutritional requirements of each individual patient were met. Any changes in the weight and body mass index [BMI] of each patient during the study period were documented. The method of delivery, composition of feed and duration of nutritional support of each feeding method were determined. The feeding methods were found to be equally effective at maintaining body weight. Patients with NG tubes in situ were more frequently prescribed a standard 1 kcal/ml feed administered via an enteral feeding pump, whereas patients with PEG tubes in situ were more frequently prescribed a high energy 1.5 Kcal/ ml feed administered by the bolus method. A number of advantages are associated with PEG feeding including greater mobility, cosmesis and quality of life. Evidence indicates the outcome of radiotherapy treatment is not as favourable if interrupted, therefore, it is essential PEG tubes are sited prior to commencing treatment, illustrating the necessity for dietetic intervention for every patient to be addressed and incorporated into the treatment plan on diagnosis of head and neck cancer before definitive management commences.
这项为期两年的前瞻性研究旨在比较两种营养支持方法的效果,即对在某地区肿瘤治疗中心接受放射治疗时无法维持营养状况的头颈癌患者实施鼻胃管(NG)和经皮内镜下胃造口术(PEG)喂养。计算了纳入研究的100名患者的营养需求,并实施了肠内喂养方案,以确保满足每名患者的营养需求。记录了研究期间每名患者体重和体重指数(BMI)的任何变化。确定了每种喂养方法的输送方式、喂养成分和营养支持持续时间。结果发现,两种喂养方法在维持体重方面同样有效。留置鼻胃管的患者更常通过肠内喂养泵给予标准的1千卡/毫升喂养液,而留置PEG管的患者更常通过推注法给予高能量的1.5千卡/毫升喂养液。PEG喂养有许多优点,包括更大的活动能力、美观和生活质量。有证据表明,如果放疗中断,治疗结果就不那么理想,因此,在开始治疗前必须放置PEG管,这说明对头颈癌患者进行饮食干预并在确定治疗方案之前将其纳入诊断后的治疗计划是必要的。