Johnson S L, Miller I
Department of Psychology, University of Miami, Coral Gables 33124-0721, USA.
J Abnorm Psychol. 1997 Aug;106(3):449-57. doi: 10.1037//0021-843x.106.3.449.
The authors of the current study examined the impact of severe negative life events on time to recovery from episodes of bipolar disorder. Although negative life events have been shown to influence relapse in bipolar disorder, research has not focused on life events and recovery in bipolar disorder. The authors recruited 67 individuals with bipolar disorder during hospitalization and conducted monthly assessments for at least 1 year. Individuals with severe negative life events took more than 3 times as long to achieve recovery as those without severe life events, and the impact of life events was not mediated by medication compliance. These results reveal that the psychosocial environment may play a much larger role in the course of bipolar disorder than previous biological models have suggested.
本研究的作者考察了严重负面生活事件对双相情感障碍发作后恢复时间的影响。尽管负面生活事件已被证明会影响双相情感障碍的复发,但此前研究尚未聚焦于双相情感障碍中的生活事件与恢复情况。作者在住院期间招募了67名双相情感障碍患者,并进行了至少为期1年的月度评估。经历严重负面生活事件的患者实现康复所需的时间是未经历严重生活事件患者的3倍多,且生活事件的影响不受药物依从性的调节。这些结果表明,社会心理环境在双相情感障碍病程中所起的作用可能比以往生物学模型所显示的要大得多。