Egleston C V, Ben Aslam H, Lambert M A
Accident and Emergency Department, Norfolk & Norwich Hospital.
J Accid Emerg Med. 1997 Jul;14(4):222-4. doi: 10.1136/emj.14.4.222.
To examine the feasibility of using expiratory capnography as an indicator of airway obstruction in non-intubated resuscitation room patients.
Patients with potential respiratory compromise admitted to the resuscitation room were assessed for widespread expiratory wheeze. This was taken as clinical evidence of airways obstruction. Expiratory capnograms of these patients and patients who had no wheeze were obtained. The traces were analysed for basic morphology and where appropriate the slope ratio (SR) between phase 1 (S1) and phase 2 (S2) of the trace was obtained.
Thirty eight patients with a variety of clinical conditions causing potential or actual respiratory impairment were studied. All patients tolerated the nasal capnogram cannulae. Twelve had no clinical evidence of airway obstruction and all had capnograms with normal morphology. Eleven of these were analysed further. The mean value for SR was 7.57 (SEM 0.18), 95% confidence interval 6.37 to 8.77. Twenty six patients had clinical evidence of airway obstruction "sharks fin" morphology. Fourteen of these were analysed to determine SR. The mean value was 31.9 (4.46), 95% CI 22.9 to 40.8. There was a significant difference in the mean value for SR between the two groups (P << 0.001).
Capnography may be used as a means of continuous respiratory monitoring in non-intubated acutely ill patients. Capnogram analysis may be used to indicate airway obstruction in these patients. Further work is required to correlate curve indices to degree of airway obstruction.
探讨在未插管的复苏室患者中,使用呼气末二氧化碳监测作为气道阻塞指标的可行性。
对入住复苏室且有潜在呼吸功能不全的患者进行广泛呼气哮鸣音评估。这被视为气道阻塞的临床证据。获取这些患者以及无哮鸣音患者的呼气末二氧化碳图。分析波形的基本形态,并在适当情况下获取波形第1阶段(S1)和第2阶段(S2)之间的斜率比(SR)。
研究了38例因各种临床情况导致潜在或实际呼吸功能损害的患者。所有患者均耐受鼻二氧化碳图插管。12例无气道阻塞的临床证据,且所有患者的二氧化碳图形态正常。其中11例进一步分析。SR的平均值为7.57(标准误0.18),95%置信区间为6.37至8.77。26例患者有气道阻塞的临床证据,呈“鲨鱼鳍”形态。其中14例进行分析以确定SR。平均值为31.9(4.46),95%置信区间为22.9至40.8。两组之间SR的平均值有显著差异(P << 0.001)。
二氧化碳监测可作为未插管急性病患者连续呼吸监测的一种手段。二氧化碳图分析可用于指示这些患者的气道阻塞情况。需要进一步开展工作,以将曲线指标与气道阻塞程度相关联。