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人类免疫缺陷病毒感染及戒毒时间对男性吸毒者人体测量指标和饮食摄入的影响

Effects of human immunodeficiency virus infection and detoxification time on anthropometric measurements and dietary intake of male drug addicts.

作者信息

Varela P, Marcos A, Ripoll S, Santacruz I, Requejo A M

机构信息

Instituto de Nutrición y Bromatología [Consejo Superior de Investigaciones Cientifícas (CSIC)], Universidad Complutense de Madrid (UCM), Spain.

出版信息

Am J Clin Nutr. 1997 Aug;66(2):509S-514S. doi: 10.1093/ajcn/66.2.509S.

DOI:10.1093/ajcn/66.2.509S
PMID:9250140
Abstract

Anthropometric measurements and dietary intakes of male drug addicts (n = 62), infected (n = 23) or not infected (n = 39) with human immunodeficiency virus (HIV), who underwent two phases of detoxification (P1:15 d to 1 mo and P2: 5-6 mo) were assessed. Body weight, weight gain during detoxification, height, body mass index, and ideal body weight were measured. A prospective food-record questionnaire was compiled and energy and nutrient contents of ingested food were determined. Food intakes were compared with dietary recommendations for the Spanish population. At the time of the study, all patients had substantial weight gains, mostly in P1. Nutrient consumption was lower in P2 (energy, protein, and lipids) and in groups not infected with HIV. In P2, lipid intake was higher in the HIV-positive than in the HIV-negative group (P < 0.05, Student's t test). Moreover, an interactive effect of HIV by phase was shown for lipid intake (P = 0.04, two-way analysis of variance). Magnesium, folate, and vitamin E intakes were lower than recommended in nearly all patients. Energy, zinc, riboflavin, and vitamin B-6 intakes were lower than recommended or were borderline. HIV infection did not have a negative effect on anthropometric measurements or on nutrient intakes. The anthropometric assessment may suggest an adequate recovery of the indexes measured in all patients, which principally took place during P1. Measurement of nutrient intakes showed certain imbalances and deficits that should be corrected.

摘要

对62名男性吸毒者进行了人体测量和饮食摄入评估,这些吸毒者感染(n = 23)或未感染(n = 39)人类免疫缺陷病毒(HIV),并经历了两个戒毒阶段(P1:15天至1个月和P2:5 - 6个月)。测量了体重、戒毒期间的体重增加、身高、体重指数和理想体重。编制了一份前瞻性食物记录问卷,并确定了摄入食物的能量和营养成分。将食物摄入量与西班牙人群的饮食建议进行了比较。在研究时,所有患者体重均有显著增加,主要发生在P1阶段。P2阶段(能量、蛋白质和脂质)以及未感染HIV的组营养消耗较低。在P2阶段,HIV阳性组的脂质摄入量高于HIV阴性组(P < 0.05,学生t检验)。此外,脂质摄入量显示出HIV与阶段之间的交互作用(P = 0.04,双向方差分析)。几乎所有患者的镁、叶酸和维生素E摄入量均低于推荐值。能量、锌、核黄素和维生素B - 6摄入量低于推荐值或处于临界值。HIV感染对人体测量指标或营养摄入没有负面影响。人体测量评估可能表明所有患者测量的指标得到了充分恢复,这主要发生在P1阶段。营养摄入测量显示存在一些应予以纠正的失衡和不足。

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