Parkman H P, Miller M A, Trate D, Knight L C, Urbain J L, Maurer A H, Fisher R S
Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania, USA.
J Clin Gastroenterol. 1997 Jun;24(4):214-9. doi: 10.1097/00004836-199706000-00006.
We have tried to correlate abnormalities in electrogastrography (EGG) and gastric emptying (GE) with symptom severity in patients with functional dyspepsia. Seventy-two patients with functional dyspepsia underwent EGG, GE, and symptom severity quantitation. EGGs were assessed for dominant frequency (DF), percentage of time of DF in the 2 to 4 cpm range, and postprandial-fasting DF power ratio. Solid-phase GE scintigraphy was assessed for 2-hour percentage retention. Symptoms of upper abdominal discomfort, early satiety, postprandial abdominal distension, nausea, vomiting, and anorexia were graded as none (0), mild (1), moderate (2), and severe (3); the sum represented a total symptom score. The EGG was abnormal in 11 of 22 (50%) patients with delayed GE compared with 11 of 50 (22%) with normal GE (p < 0.025). The total symptom scores were higher in patients with both delayed GE and abnormal EGG compared with patients with normal GE and EGG, normal GE and abnormal EGG, and delayed GE and normal EGG. We conclude that EGG abnormalities are more common in dyspeptic patients with delayed GE. Patients with both delayed GE and abnormal EGG have more severe symptoms. Our results suggest that EGG and GE complement each other in correlating symptoms to gastric dysmotility.
我们试图将功能性消化不良患者的胃电图（EGG）和胃排空（GE）异常与症状严重程度相关联。72例功能性消化不良患者接受了EGG、GE检查及症状严重程度量化评估。评估EGG的主频（DF）、2至4次/分钟范围内DF的时间百分比以及餐后-空腹DF功率比。通过固相GE闪烁扫描评估2小时滞留百分比。上腹部不适、早饱、餐后腹胀、恶心、呕吐和厌食等症状分为无（0）、轻度（1）、中度（2）和重度（3）；各项症状得分总和即为总症状评分。GE延迟的22例患者中有11例（50%）EGG异常，而GE正常的50例患者中有11例（22%）EGG异常（p < 0.025）。与GE和EGG均正常、GE正常但EGG异常以及GE延迟但EGG正常的患者相比，GE延迟且EGG异常的患者总症状评分更高。我们得出结论，EGG异常在GE延迟的消化不良患者中更为常见。GE延迟且EGG异常的患者症状更严重。我们的结果表明，在将症状与胃动力相关联方面，EGG和GE相互补充。
