Julander I, Petrini B
Department of Infectious Diseases, Huddinge Hospital, Sweden.
Scand J Infect Dis. 1997;29(3):320-2. doi: 10.3109/00365549709019055.
We report a case of Penicillium marneffei infection, acquired in Thailand, in a Swedish HIV-infected immunodeficient heroin addict. This is the first case of penicilliosis marneffei diagnosed in Sweden. The patient had fever without focal symptoms. Cultures from bronchoalveolar lavage fluid and a mediastinal lymph node yielded the dimorphic fungus Penicillium marneffei. Treatment with amphotericin B followed by itraconazole was successful. Penicillium marneffei infection should be considered in HIV patients with fever who have visited Southeast Asia, especially northern Thailand and southern China.
我们报告了一例马尔尼菲青霉感染病例,该病例发生在泰国,患者为一名感染艾滋病毒的瑞典免疫缺陷海洛因成瘾者。这是瑞典确诊的首例马尔尼菲青霉病病例。患者发热但无局部症状。支气管肺泡灌洗 fluid 和纵隔淋巴结培养出双相真菌马尔尼菲青霉。先用两性霉素 B 治疗,后用伊曲康唑治疗,取得成功。对于去过东南亚,尤其是泰国北部和中国南部且发热的艾滋病毒患者,应考虑马尔尼菲青霉感染。 (注:原文中“bronchoalveolar lavage fluid”表述有误,正确的是“bronchoalveolar lavage fluid”,直译为“支气管肺泡灌洗液体”,这里意译为“支气管肺泡灌洗标本”更合适,但按要求未作修改)