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一名瑞典感染艾滋病毒的免疫缺陷麻醉品成瘾者发生马尔尼菲青霉感染。

Penicillium marneffei infection in a Swedish HIV-infected immunodeficient narcotic addict.

作者信息

Julander I, Petrini B

机构信息

Department of Infectious Diseases, Huddinge Hospital, Sweden.

出版信息

Scand J Infect Dis. 1997;29(3):320-2. doi: 10.3109/00365549709019055.

Abstract

We report a case of Penicillium marneffei infection, acquired in Thailand, in a Swedish HIV-infected immunodeficient heroin addict. This is the first case of penicilliosis marneffei diagnosed in Sweden. The patient had fever without focal symptoms. Cultures from bronchoalveolar lavage fluid and a mediastinal lymph node yielded the dimorphic fungus Penicillium marneffei. Treatment with amphotericin B followed by itraconazole was successful. Penicillium marneffei infection should be considered in HIV patients with fever who have visited Southeast Asia, especially northern Thailand and southern China.

摘要

我们报告了一例马尔尼菲青霉感染病例,该病例发生在泰国,患者为一名感染艾滋病毒的瑞典免疫缺陷海洛因成瘾者。这是瑞典确诊的首例马尔尼菲青霉病病例。患者发热但无局部症状。支气管肺泡灌洗 fluid 和纵隔淋巴结培养出双相真菌马尔尼菲青霉。先用两性霉素 B 治疗,后用伊曲康唑治疗,取得成功。对于去过东南亚,尤其是泰国北部和中国南部且发热的艾滋病毒患者,应考虑马尔尼菲青霉感染。 (注:原文中“bronchoalveolar lavage fluid”表述有误,正确的是“bronchoalveolar lavage fluid”,直译为“支气管肺泡灌洗液体”,这里意译为“支气管肺泡灌洗标本”更合适,但按要求未作修改)

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