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北京一非地方性流行地区 AIDS 患者出现疣状损害的播散性马尔尼菲青霉感染。

Disseminated Penicillium Marneffei infection with verrucoid lesions in an AIDS patient in Beijing, a non-endemic region.

机构信息

Department of Dermatology, Peking University People's Hospital, Beijing, 100044, China.

出版信息

Eur J Dermatol. 2010 May-Jun;20(3):378-80. doi: 10.1684/ejd.2010.0904. Epub 2010 Feb 5.

Abstract

Penicillium marneffei (PM) infection is prevalent in South-East Asia and Southern China and has been considered an acquired immunodeficiency syndrome (AIDS)-defining disease. This report focused on the verrucoid proliferative lesions of P. marneffei infection in a 34-year-old Chinese female AIDS patient from a non-endemic region. She recovered after receiving intravenous amphotericin B followed by oral itraconazole therapy. At the same time, highly active antiretroviral therapy (HAART) was also started. She responded very well to the treatment.

摘要

马尔尼菲青霉(PM)感染在东南亚和中国南方流行,被认为是获得性免疫缺陷综合征(AIDS)的一种定义性疾病。本报告重点介绍了一位来自非流行地区的 34 岁中国女性 AIDS 患者的 PM 感染疣状增生性病变。该患者接受静脉注射两性霉素 B 后序贯口服伊曲康唑治疗后痊愈。同时,开始了高效抗逆转录病毒治疗(HAART)。她对治疗反应非常好。

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