Bélanger L F
J Nutr. 1977 Dec;107(12):2164-70. doi: 10.1093/jn/107.12.2164.
Comparative counts of Alcian Blue-Basic Fuchsin-stained mast cells of the facial skin and bone marrow have been made in young rats of different sexes and strains, fed a diet deficient in magnesium (0.8 to 1 mg/100 g dry weight) for 4 weeks. Normal rats fed a magnesium-supplemented diet (65 mg/100 g dry weight) had about three times as many mast cells in the tibial metaphysis as in the facial skin. In both males and females fed the Mg-deficient diet, the marrow mast cells increased five to six times, while their number was concomitantly decreased in the skin. The marrow mast cells became also polymorphic, an indication of a possible preferential renewal site. Gonadectomy in the males had no effect on the above pattern. The administration of large doses of testosterone to males and estradiol to females depressed the mast cell population increase in the bone marrow and at the same time, moderated the loss of skin mast cells.
对不同性别和品系的幼鼠进行了比较计数，这些幼鼠食用缺镁（0.8至1毫克/100克干重）饮食4周，然后对其面部皮肤和骨髓中阿尔辛蓝-碱性品红染色的肥大细胞进行计数。食用补充镁饮食（65毫克/100克干重）的正常大鼠，胫骨近端骨骺中的肥大细胞数量约为面部皮肤中的三倍。在食用缺镁饮食的雄性和雌性大鼠中，骨髓肥大细胞增加了五到六倍，而皮肤中的肥大细胞数量则相应减少。骨髓肥大细胞也变得多形性，这表明可能存在优先更新部位。雄性大鼠去势对上述模式没有影响。给雄性大鼠注射大剂量睾酮，给雌性大鼠注射雌二醇，可抑制骨髓中肥大细胞数量的增加，同时减轻皮肤肥大细胞的损失。
