Akiyama H, Yoshinaga H, Endou M, Tanikawa S, Sakamaki H, Tanoue K, Onozawa Y
Hematology Division, Tokyo Metropolitan Komagome Hospital, Bunkyo-ku, Japan.
Bone Marrow Transplant. 1997 Aug;20(3):261-3. doi: 10.1038/sj.bmt.1700875.
Thrombotic microangiopathy (TMA) is one of the complications of bone marrow transplantation (BMT) which includes hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). Red cell fragmentation is the most consistent laboratory finding. We present a case of TMA with endothelial damage but without the signs of hemolysis. The patient was not receiving cyclosporine. Partial activation of platelets was also observed. This case represents a new form of TMA in transplant recipients.
血栓性微血管病（TMA）是骨髓移植（BMT）的并发症之一，其中包括溶血性尿毒症综合征（HUS）和血栓性血小板减少性紫癜（TTP）。红细胞碎片是最常见的实验室检查结果。我们报告一例伴有内皮损伤但无溶血迹象的TMA病例。该患者未接受环孢素治疗。还观察到血小板部分活化。该病例代表了移植受者中TMA的一种新形式。
