Parker M M, Peruzzi W
Department of Pediatrics, SUNY at Stony Brook, NY 11794-8111, USA.
New Horiz. 1997 Aug;5(3):228-32.
To review the literature addressing use of the pulmonary artery catheter (PAC) in patients with sepsis and septic shock.
All pertinent English language articles dealing with the use of pulmonary artery catheterization in patients with sepsis and septic shock were retrieved from 1984 through 1996.
Articles were chosen for review if the use of pulmonary artery catheterization in patients with sepsis/septic shock was studied or reviewed.
From the articles selected, information was obtained about changes in therapy and changes in outcome associated with PAC use in patients with sepsis/septic shock.
Inadequate evidence exists to accurately determine if PAC use improves outcome in patients with sepsis/septic shock. Attempting to achieve supranormal hemodynamic variables in patients with septic shock is not warranted.
Based largely upon expert opinion, PAC use may be appropriate in patients with septic shock unresponsive to early resuscitative measures. Maintenance of normal hemodynamics in this group of patients appears to be the appropriate goal. Research is needed to determine the proper role of the PAC in patients with sepsis/septic shock.
回顾关于肺动脉导管（PAC）在脓毒症和脓毒性休克患者中应用的文献。
检索了1984年至1996年间所有涉及肺动脉导管插入术在脓毒症和脓毒性休克患者中应用的相关英文文章。
若文章对脓毒症/脓毒性休克患者使用肺动脉导管插入术进行了研究或综述，则选择其进行回顾。
从所选文章中，获取了与脓毒症/脓毒性休克患者使用PAC相关的治疗变化和结局变化信息。
尚无充分证据准确确定使用PAC是否能改善脓毒症/脓毒性休克患者的结局。对于脓毒性休克患者，试图实现超常血流动力学变量是没有必要的。
很大程度上基于专家意见，PAC的使用可能适用于对早期复苏措施无反应的脓毒性休克患者。维持这组患者的正常血流动力学似乎是合适的目标。需要开展研究以确定PAC在脓毒症/脓毒性休克患者中的恰当作用。
