Velissaris Dimitrios, Karamouzos Vasilios, Kotroni Ioanna, Pierrakos Charalampos, Karanikolas Menelaos
Internal Medicine Department, University Hospital of Patras, Greece.
Coronary Care Unit, University Hospital of Patras, Greece.
J Clin Med Res. 2016 Nov;8(11):769-776. doi: 10.14740/jocmr2719w. Epub 2016 Sep 29.
This article was to review the literature regarding the use of the pulmonary artery catheter (PAC) in the management of patients with sepsis and septic shock. A PubMed search was conducted in order to identify publications evaluating the use of PAC as a tool for management and therapeutic guidance in patients with sepsis. The bibliographies of all identified publications were reviewed for additional relevant references. Much information is identified in the literature regarding the indications for pulmonary artery catheterization in the assessment and treatment of patients with sepsis. Although the PAC has been widely used for many years, there is no clear benefit with regard to outcome, and there is controversy regarding its use. It is not clear that use of the PAC contributes to reduced morbidity and mortality in patients with sepsis. The role of the PAC is becoming less clear, as newer, non-invasive techniques are developed for hemodynamic assessment of sepsis patients. Large, well-designed clinical trials are needed to better assess the role and potential benefit from use of the PAC in sepsis.
本文旨在综述关于肺动脉导管(PAC)在脓毒症和脓毒性休克患者管理中的应用的文献。进行了PubMed检索,以识别评估PAC作为脓毒症患者管理和治疗指导工具的使用情况的出版物。对所有已识别出版物的参考文献进行了审查,以获取更多相关参考文献。文献中发现了许多关于肺动脉导管插入术在脓毒症患者评估和治疗中的适应证的信息。尽管PAC多年来一直被广泛使用,但在结局方面没有明确的益处,并且其使用存在争议。目前尚不清楚使用PAC是否有助于降低脓毒症患者的发病率和死亡率。随着用于脓毒症患者血流动力学评估的更新的非侵入性技术的发展,PAC的作用变得越来越不明确。需要进行大型、设计良好的临床试验,以更好地评估PAC在脓毒症中的作用和潜在益处。