一种适用于自动化系统血型鉴定的鼠源单克隆抗N抗体，即BIRMA-N。
A murine monoclonal anti-N, BIRMA-N, suitable for blood grouping in an automated system.
作者信息
Thompson J M, McDonald D F
机构信息
West Midlands Regional Transfusion Centre, Birmingham, U.K.
出版信息
Transfus Med. 1991 Dec;1(4):239-43. doi: 10.1111/j.1365-3148.1991.tb00039.x.
BIRMA-N, a murine monoclonal anti-N antibody of the IgG1 subclass, was assessed for suitability as a blood grouping reagent on the Olympus PK7100 automated blood grouping machine. At a selected dilution and over the pH range 5.0-8.0, the antibody performed accurately in this system as confirmed by parallel manual testing of donor blood samples with human anti-N and commercial monoclonal anti-N reagents. These findings show BIRMA-N to be extremely suitable for N typing blood samples in an automated system providing a convenient, objective and cost-effective method for large scale typing of the blood donor population.
BIRMA-N是一种IgG1亚类的鼠源单克隆抗-N抗体，在奥林巴斯PK7100自动血型分析仪上评估其作为血型鉴定试剂的适用性。在选定的稀释度以及pH值5.0 - 8.0范围内，通过使用人抗-N和商业单克隆抗-N试剂对供血者血样进行平行手工检测证实，该抗体在该系统中表现准确。这些结果表明，BIRMA-N非常适合在自动化系统中对血样进行N血型鉴定，为大规模血型鉴定献血人群提供了一种方便、客观且经济高效的方法。
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