Spitznas M, Leuenberger R
Klin Monbl Augenheilkd. 1977 Sep;171(3):410-20.
Analyzing the findings of 45 patients with primary epiretinal gliosis in 51 otherwise entirely healthy eyes, the clinical features of the disease are elaborated. The disorder is characterized by the occurance of a glial membrane covering the retina in the area of the posterior pole and leading to a distorsion of the posterior pole and leading to a distorsion of the subjacent and surrounding tissues. Most frequently, the foveal region is involved, but the foveola is often spared. With increasing distance from the center the frequency of involvement decreases. Only in very rare cases the membrane extends beyond a distance of 5,5 mm from the center of the retina. The density of the membrane varies from case to case. Average visual acuity of the eyes evaluated in this study was 0,45. In no case it was worse than 0,05. The incidence of the disease increased with both increasing myopia and hyperopia. The average age of the patients was 55 years. There was no predominance of either men or women. The glia cells which compose the membrane originate from the innermost layers of the retina, from where they extend on the retinal surface through a defect in the inner limiting membrane. The reason for the formation of the defects is not yet understood. It is also unknown if the presence of such defects is absolutely necessary for the development of this condition.
通过分析51只完全健康眼睛中45例原发性视网膜前胶质增生患者的检查结果，阐述了该疾病的临床特征。该病症的特点是在后极部区域出现覆盖视网膜的胶质膜，导致后极部变形，并使相邻及周围组织变形。最常累及黄斑区，但黄斑小凹通常未受影响。离中心越远，受累频率越低。仅在极少数情况下，膜会延伸至距视网膜中心5.5毫米以外的区域。膜的密度因病例而异。本研究中所评估眼睛的平均视力为0.45。无一例视力差于0.05。该疾病的发病率随近视和远视程度的增加而升高。患者的平均年龄为55岁。男女比例无明显差异。构成该膜的胶质细胞起源于视网膜的最内层，它们通过内界膜的缺损在视网膜表面延伸。缺损形成的原因尚不清楚。同样未知的是，这种缺损的存在对于该病症的发展是否绝对必要。
