Piccolino Felice Cardillo, De La Longrais Roberta Rigault, Manea Marilisa, Cicinelli Simonetta
Fondazione per la Macula Onlus, Genova, Italy.
Retina. 2008 Jul-Aug;28(7):1008-12. doi: 10.1097/IAE.0b013e31816b4b86.
To study the pattern of cystoid retinal changes in the posterior fundi of eyes with chronic central serous chorioretinopathy (CSC) using optical coherence tomography (OCT).
We retrospectively studied 34 eyes with chronic CSC and cystoid retinal changes at the posterior pole documented by OCT. We analyzed the distribution of cystoid retinal changes with respect to the fovea and chorioretinal lesions.
Generally, cystoid retinal changes occurred in the papillomacular region (21 eyes); foveal involvement was observed in 20 eyes. Large cystoid changes in the central macula with concentric perifoveal lesion extension were detected in three eyes. Cystoid changes tended to occur where the retina adhered to subretinal fibrosis, large laser scars, or spontaneous atrophy of the retinal pigment epithelium and the choroid. Visual acuity ranged from 20/20 to 20/400. In nine eyes in which the cystoid changes spared the foveal center, visual acuity was 20/40 or better.
Cystoid retinal degeneration in eyes with chronic CSC was distributed outside of the fovea and was not necessarily associated with severely reduced visual acuity. "Posterior cystoid retinal degeneration" defines this pathologic pattern appropriately. OCT findings suggest that intraretinal exudation and cystoid changes in chronic CSC develop through the formation of chorioretinal adherences.
使用光学相干断层扫描（OCT）研究慢性中心性浆液性脉络膜视网膜病变（CSC）患者眼后极部囊样视网膜改变的模式。
我们回顾性研究了34只患有慢性CSC且经OCT记录有后极部囊样视网膜改变的眼睛。我们分析了囊样视网膜改变相对于黄斑中心凹和脉络膜视网膜病变的分布情况。
一般来说，囊样视网膜改变发生在视乳头黄斑区（21只眼）；20只眼观察到黄斑中心凹受累。3只眼中检测到黄斑中心有大的囊样改变并伴有同心性的黄斑周围病变扩展。囊样改变倾向于发生在视网膜与视网膜下纤维化、大片激光瘢痕或视网膜色素上皮和脉络膜自发性萎缩粘连的部位。视力范围为20/20至20/400。在9只囊样改变未累及黄斑中心凹的眼中，视力为20/40或更好。
慢性CSC患者眼中的囊样视网膜变性分布在黄斑中心凹以外，不一定与严重视力下降相关。“后部囊样视网膜变性”恰当地定义了这种病理模式。OCT检查结果表明，慢性CSC中的视网膜内渗出和囊样改变是通过脉络膜视网膜粘连的形成而发展的。
